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American Society of Microbiology ABMM Sample Questions:

1. A fungal isolate grown from a blood culture at 37°C shows budding yeast cells. When subcultured to cornmeal agar with Tween 80 and incubated at 25°C, it produces pseudohyphae and terminal chlamydospores.
Growth on CHROMagar Candida yields green colonies. This organism is most likely:

A) Candida parapsilosis
B) Candida albicans
C) Cryptococcus neoformans
D) Candida glabrata

2. A clinical microbiology laboratory is investigating a cluster of bloodstream infections caused by Staphylococcus aureus. To differentiate between community-associated (CA-MRSA) and healthcare- associated (HA-MRSA) strains, they may look for the presence of:

A) The mecA gene, which is common to both CA-MRSA and HA-MRSA.
B) Specific staphylococcal cassette chromosome mec (SCCmec) types, such as SCCmec IV or V inCA- MRSA.
C) Panton-Valentine leukocidin (PVL) toxin genes, which are exclusively found in HA-MRSA.
D) Resistance to non-beta-lactam antibiotics, which is more common in CA-MRSA.

3. Lyme disease, characterized initially by erythema migrans, is caused by Borrelia burgdorferi. What is the primary arthropod vector responsible for transmitting this spirochete to humans in the Northeastern United States?

A) Amblyomma americanum (Lone Star tick)
B) Pulex irritans (Human flea)
C) Ixodes scapularis (Blacklegged tick)
D) Dermacentor variabilis (American dog tick)

4. A patient with a history of exposure to bats in a cave develops progressive neurological symptoms, including hydrophobia. The MOST likely viral etiology is:

A) West Nile virus
B) Rabies virus
C) Japanese encephalitis virus
D) Herpes simplex virus encephalitis

5. A patient with a history of chronic obstructive pulmonary disease (COPD) experiences an acute exacerbation.
Sputum culture grows numerous Gram-negative coccobacilli that are oxidase-positive and grow on chocolate agar but not on sheep blood agar. The MOST likely organism is:

A) Moraxella catarrhalis
B) Haemophilus influenzae
C) Legionella pneumophila
D) Streptococcus pneumoniae

Solutions: